Article
The Clinicopathological Impact of Granulocyte-Macrophage Colony-Stimulating Factor Gene Expression and Different Molecular Prognostic Biomarkers in Egyptian Acute Myeloid Leukemia Patients.
Asian Pacific journal of cancer prevention : APJCP - 1 Jul 2020
Nagdy Bassant, Kassem Hebatallah A, Abdel-Ghaffar Abdel-Rahman B, Seoudi Dina M, Kassem Neemat M
Abstract excerpt
BACKGROUND: Acute myeloid leukemia (AML) is characterized by clonal expansion of myeloid precursors with diminished capacity for differentiation. It develops as the consequence of a series of genetic changes in a hematopoietic precursor cell. Purpose This study aimed to investigate the correlation between GM-CSF gene expression and different molecular prognostic markers such as FLT3-ITD, NPM1 mutation A and CEBPA...
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