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Prognostic factors for acute myeloid leukaemia in adults - biological significance and clinical use

1 Feb 2014

Abstract excerpt

Acute myeloid leukaemia (AML) is a heterogeneous disease. Prognosis of AML is influenced both by patient-specific as well as disease-specific factors. Age is the most prominent patient-specific risk factor, while chromosomal aberrations are the strongest disease-specific risk factors. For patients with cytogenetically normal AML, prognosis can be specified by mutational status of the genes NPM1, FLT3 and CEBPA. A...

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PMID: 24484469
DOI: 10.1111/bjh.12750

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