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Article

FLT3-ITD Mutations in Egyptian Patients of Acute Myeloid Leukemia: Correlation with Cytogenetic, FAB Subgroups and Prognosis.

Clinical laboratory - 1 May 2017

Adnan-Awad Shady, Gaber Ola, Eltokhy Soad A, Mourad Dalia, Amer Mariam, Kandeel Eman Z, Eldesouky Ihab

Abstract excerpt

BACKGROUND: FLT3-ITD mutations are common in AML subgroups, particularly in Acute Promyelocytic Leukemia (APL). It infers poor prognosis in AML patients; however, its prognostic value in APL is still controversial. We aimed to assess the distribution and prognostic value of FLT3-ITD mutation within AML subgroups, focusing on APL. METHODS: In NCI, Cairo University, 346 newly diagnosed AML patients were included....

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Identifiers

PMID: 28627830
DOI: 10.7754/Clin.Lab.2017.170121

Genes

FLT3

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