Article
Gene expression profiling in acute myeloid leukaemia.
The Netherlands journal of medicine - 1 Apr 2011
de Jonge H J M, Huls G, de Bont E S J M
Abstract excerpt
Acute myeloid leukaemia (AML) is a heterogeneous disease characterised by clonal malignant haematopoiesis with a differentiation arrest and excessive proliferation of leukaemic blasts. Over the past decades, the heterogeneity of AML has been illustrated by evolving classifications based on morphology (French-American-British classification (FAB classification), cytogenetic abnormalities (e.g. t(8;21),...
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