Article
NPM1 and FLT3 mutations in acute myeloid leukemia with normal karyotype: Indian perspective.
Indian journal of pathology & microbiology - 1 Jan 2000
Sazawal Sudha, Singh Neha, Jain Sonal, Chhikara Sunita, Chaubey Rekha, Bhattacharyya Jina, Saikia Kandarpa Kr, Mahapatra Manoranjan, Saxena Renu
Abstract excerpt
BACKGROUND: FLT3-ITD and NPM1 mutations are considered to be the major determinants of the patient response to therapy and outcome. The primary aim of this study was to establish the correlation between these molecular mutations and the clinico-hematologic parameters as well as the prognostic outcome of the Indian acute myeloid leukemia (AML) patients. MATERIALS AND METHODS: This prospective study involved newly...
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