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Development of attenuated live vaccine candidates against swine brucellosis in a non-zoonotic B. suis biovar 2 background

23 Jul 2020

Abstract excerpt

Abstract Brucellais a genus of gram-negative bacteria that cause brucellosis. B. abortusandB. melitensisinfect domestic ruminants whileB. suis(biovars 1–3) infect swine, and all these bacteria butB. suisbiovar 2 are zoonotic. Live attenuatedB. abortusS19 andB. melitensisRev1 are effective vaccines in domestic ruminants, though both can infect humans. However, there is no swine brucellosis vaccine. Here, we...

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Share to Brucella: diagnosis, epidemiology, treatment
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PMID: 32703299
DOI: 10.1186/s13567-020-00815-8

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