Article
Comparative genomic analysis between newly sequenced Brucella suis Vaccine Strain S2 and the Virulent Brucella suis Strain 1330.
BMC genomics - 20 Sept 2016
Di Dong-Dong, Jiang Hai, Tian Li-Li, Kang Jing-Li, Zhang Wen, Yi Xin-Ping, Ye Feng, Zhong Qi, Ni Bo, He You-Yu, Xia Lin, Yu Yao, Cui Bu-Yun, Mao Xiang, Fan Wei-Xing
Abstract excerpt
BACKGROUND: Brucellosis is a bacterial disease caused by Brucella infection. In the late fifties, Brucella suis vaccine strain S2 with reduced virulence was obtained by serial transfer of a virulent B. suis biovar 1 strain in China. It has been widely used for vaccination in China since 1971. Until now, the mechanisms underlie virulence attenuation of S2 are still unknown. RESULTS: In this paper, the whole genome...
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