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Brucella melitensis M5-90Δbp26 as a potential live vaccine that allows for the distinction between natural infection and immunization

8 May 2017

Abstract excerpt

Brucella is Gram-negative intracellular bacterial pathogen that infects humans and animals and contributes to great economic losses in developing countries. Presently, live attenuated Brucella vaccines (Brucella melitensis M5-90) are the most effective means of brucellosis control and prevention in animals. However, these vaccines have several drawbacks, such as an inability to distinguish between a natural...

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PMID: 28482164
DOI: 10.1139/cjm-2017-0179

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