Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protection of BALB/c mice against homologous and heterologous species of Brucella by rough strain vaccines derived from Brucella melitensis and Brucella suis biovar 4.

American journal of veterinary research - 1 May 1996

Winter A J, Schurig G G, Boyle S M, Sriranganathan N, Bevins J S, Enright F M, Elzer P H, Kopec J D

Abstract excerpt

OBJECTIVE: To evaluate stable rough mutants derived from Brucella melitensis 16M and B suis 2579 (biovar 4) as vaccines against homologous and heterologous Brucella spp in the BALB/c mouse model. DESIGN, ANIMALS, AND PROCEDURE: Rough mutants VTRM1 and VTRS1 were obtained from B melitensis 16M and B suis 2579, respectively, by allelic exchange of rfbU gene encoding mannosyltransferase with a Tn5-disrupted rfbU...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Antibodies, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, Viral

Share to Blotting, Western

Share to Cattle

Share to Mice, Inbred BALB C

Share to Mutation

Source

Identifiers

PMID: 8723881

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protection of BALB/c mice against homologous and heterologous species of Brucella by rough strain vaccines derived from Brucella melitensis and Brucella suis biovar 4.PMID 8723881Read ↗

Protective properties of rifampin-resistant rough mutants of Brucella melitensis.Semantic proximity Read ↗

Rev1 wbdR tagged vaccines against Brucella ovisSemantic proximity Read ↗

Evaluation of Brucella melitensis B115 as rough-phenotype vaccine against B. melitensis and B. ovis infections.Semantic proximity Read ↗

Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export.Semantic proximity Read ↗

Enhanced efficacy of recombinant Brucella abortus RB51 vaccines against B. melitensis infection in mice.Semantic proximity Read ↗

Complementation of Brucella abortus RB51 with a functional wboA gene results in O-antigen synthesis and enhanced vaccine efficacy but no change in rough phenotype and attenuation.Semantic proximity Read ↗

Brucella melitensis Rev1Δwzm: Placental pathogenesis studies and safety in pregnant ewesSemantic proximity Read ↗

Genomic Analysis of Natural Rough Brucella melitensis Rev.1 Vaccine Strains: Identification and Characterization of Mutations in Key Genes Associated with Bacterial LPS Biosynthesis and Virulence.Semantic proximity Read ↗

Immunization with a single dose of a microencapsulated Brucella melitensis mutant enhances protection against wild-type challenge.Semantic proximity Read ↗

Protective efficacy and safety of Brucella melitensis 16MΔmucR against intraperitoneal and aerosol challenge in BALB/c mice.Semantic proximity Read ↗

The Brucella abortus S19 DeltavjbR live vaccine candidate is safer than S19 and confers protection against wild-type challenge in BALB/c mice when delivered in a sustained-release vehicle.Semantic proximity Read ↗

A19Δbpe275 emerges as a safer live attenuated vaccine candidateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.