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Rev1 wbdR tagged vaccines against Brucella ovis

15 Nov 2019

Abstract excerpt

Sheep brucellosis is a worldwide extended disease caused by B. melitensis and B. ovis, two species respectively carrying smooth or rough lipopolysaccharide. Vaccine B. melitensis Rev1 is used against B. melitensis and B. ovis but induces an anti-smooth-lipopolysaccharide response interfering with B. melitensis serodiagnosis, which precludes its use against B. ovis where B. melitensis is absent. In mice, Rev1...

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PMID: 31730501
DOI: 10.1186/s13567-019-0714-3

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