Article
Functional genomics in hypertension.
Current opinion in nephrology and hypertension - 1 Mar 2006
McBride Martin W, Graham Delyth, Delles Christian, Dominiczak Anna F
Abstract excerpt
PURPOSE OF REVIEW: Essential hypertension is a complex polygenetic disease with a major impact on health worldwide. Despite earlier detection of promising candidate genes, only recent advances in genotyping technology and new approaches to examining gene and protein function have provided the tools to unravel the genetic basis of hypertension. RECENT FINDINGS: In humans, genome-wide scans resulted in the...
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