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Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression.

Biological psychiatry - 15 Jul 2006

Yamada Kazuo, Hattori Eiji, Iwayama Yoshimi, Ohnishi Tetsuo, Ohba Hisako, Toyota Tomoko, Takao Hitomi, Minabe Yoshio, Nakatani Noriaki, Higuchi Teruhiko, Detera-Wadleigh Sevilla D, Yoshikawa Takeo

Abstract excerpt

BACKGROUND: Genetic variations in the serotonin receptor 3A (HTR3A) and 3B (HTR3B) genes, positioned in tandem on chromosome 11q23.2, have been shown to be associated with psychiatric disorders in samples of European ancestry. But the polymorphisms highlighted in these reports map to different locations in the two genes, therefore it is unclear which gene exerts a stronger effect on susceptibility. METHODS: To...

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Identifiers

PMID: 16487942
DOI: 10.1016/j.biopsych.2005.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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