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Article

Association between the 5' UTR variant C178T of the serotonin receptor gene HTR3A and bipolar affective disorder.

Pharmacogenetics - 1 Aug 2001

Niesler B, Flohr T, Nöthen M M, Fischer C, Rietschel M, Franzek E, Albus M, Propping P, Rappold G A

Abstract excerpt

Serotonin receptor type 3 is a ligand-gated ion channel implicated in behavioural disorders. Our objective was to identify nucleotide variants in a specific portion of the 5' region of the serotonin receptor gene (HTR3A) containing upstream open reading frames (uORFs) and to investigate their effect on bipolar disease. Mutations in uORFs have been recently shown to cause disease by changing expression on the...

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Source

Identifiers

PMID: 11505217
DOI: 10.1097/00008571-200108000-00002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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