Article
Association between the 5-HTR1B gene polymorphisms and alcohol dependence in a Han Chinese population.
Brain research - 28 Feb 2011
Cao Jin-Xia, Hu Jian, Ye Xiang-Mei, Xia Yian, Haile Colin A, Kosten Thomas R, Zhang Xiang Yang
Abstract excerpt
The human serotonin receptor 1B (HRT1B) plays an important role in regulating serotonin release. Previous research has suggested that the genetic variation of the HTR1B gene may confer susceptibility to alcoholism or some subtypes of alcohol dependence, but the evidence has been inconsistent. The aim of the present study is to examine whether polymorphic variants of the HTR1B gene are associated with alcohol...
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