Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in the regulatory region of the human serotonin 5-HT2A receptor gene (HTR2A) influence gene expression.

Biological psychiatry - 15 Jan 2007

Myers Regina L, Airey David C, Manier D Hal, Shelton Richard C, Sanders-Bush Elaine

Abstract excerpt

BACKGROUND: Genomic variation in the regulatory region of the serotonin (5-HT) 2A receptor gene (HTR2A) may contribute to altered levels of 5-HT2A receptor and to psychiatric disease. METHODS: Frequency and linkage disequilibrium (LD) were determined for promoter single nucleotide polymorphisms (...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epistasis, Genetic
Share to Gene Expression
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Promoter Regions, Genetic

Share to Receptor, Serotonin, 5-HT2A

Share to Regulatory Sequences, Nucleic Acid

Share to RNA, Messenger

Source

Identifiers

PMID: 16697352
DOI: 10.1016/j.biopsych.2005.12.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16697352-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in the regulatory region of the human serotonin 5-HT2A receptor gene (HTR2A) influence gene expression.PMID 16697352Read ↗

Effects of HTR1B 3' region polymorphisms and functional regions on gene expression regulationSemantic proximity Read ↗

Effects of HTR1B 3' region polymorphisms and functional regions on gene expression regulation.Semantic proximity Read ↗

The -1438A/G polymorphism in the 5-hydroxytryptamine type 2A receptor gene affects promoter activity.Semantic proximity Read ↗

Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex.Semantic proximity Read ↗

Functional polymorphisms and transcriptional analysis in the 5' region of the human serotonin receptor 1B gene (HTR1B) and their associations with psychiatric disorders.Semantic proximity Read ↗

Functional polymorphisms and transcriptional analysis in the 5' region of the human serotonin receptor 1B gene (HTR1B) and their associations with psychiatric disordersSemantic proximity Read ↗

Polymorphic DNA repeats in the human serotonin transporter gene locus, predisposing to behavioural disorders, emerge as functional regulators of gene expressionSemantic proximity Read ↗

Polymorphisms in the 5'-untranslated region of the human serotonin receptor 1B (HTR1B) gene affect gene expression.Semantic proximity Read ↗

Role of the 5-HTTLPR and SNP Promoter Polymorphisms on Serotonin Transporter Gene Expression: a Closer Look at Genetic Architecture and In Vitro Functional Studies of Common and Uncommon Allelic Variants.Semantic proximity Read ↗

Functional characterization of the human TPH2 5' regulatory region: untranslated region and polymorphisms modulate gene expression in vitro.Semantic proximity Read ↗

Association between major depressive disorder and the -1438A/G polymorphism of the serotonin 2A receptor gene.Semantic proximity Read ↗

5-HT1A receptor (HTR1A) 5' region haplotypes significantly affect protein expression in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.