Article
A unified framework for association and prediction from vertex-wise grey-matter structure.
Human brain mapping - 1 Oct 2020
Couvy-Duchesne Baptiste, Strike Lachlan T, Zhang Futao, Holtz Yan, Zheng Zhili, Kemper Kathryn E, Yengo Loic, Colliot Olivier, Wright Margaret J, Wray Naomi R, Yang Jian, Visscher Peter M
Abstract excerpt
The recent availability of large-scale neuroimaging cohorts facilitates deeper characterisation of the relationship between phenotypic and brain architecture variation in humans. Here, we investigate the association (previously coined morphometricity) of a phenotype with all 652,283 vertex-wise measures of cortical and subcortical morphology in a large data set from the UK Biobank (UKB; N = 9,497 for discovery, N...
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