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Imaging niacin trafficking with positron emission tomography reveals in vivo monocarboxylate transporter distribution

6 Jul 2020

Abstract excerpt

A sufficient dietary intake of the vitamin niacin is essential for normal cellular function. Niacin is transported into the cells by the monocarboxylate transporters: sodium-dependent monocarboxylate transporter (SMCT1 and SMCT2) and monocarboxylate transporter (MCT1). Despite the importance of niacin in biological systems, surprisingly, its in vivo biodistribution and trafficking in living organisms has not been...

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PMID: 32683248
DOI: 10.1016/j.nucmedbio.2020.07.002

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