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Direct Carbon Isotope Exchange of Pharmaceuticals via Reversible Decyanation

2021-02-18

Abstract excerpt

The incorporation of carbon-14 allows tracking of organic molecules and provides vital knowledge on their fate. This information is critical in pharmaceutical development, crop science and human food safety evaluation. Herein, a transition-metal-catalyzed procedure enabling carbon isotope exchange on aromatic nitriles is described. Utilizing the radiolabeled precursor Zn([ 14 C]CN) 2 , this protocol allows the i...

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Literature Corpus work
e8974dbd-b67d-5ab8-a2ce-239919bdda7c
DOI
10.26434/chemrxiv.14049896.v1
Open publication

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Direct Carbon Isotope Exchange of Pharmaceuticals via Reversible DecyanationDOI 10.26434/chemrxiv.14049896.v1
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