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Article

Radiolabeling of HTE1PA: A new monopicolinate cyclam derivative for Cu-64 phenotypic imaging. In vitro and in vivo stability studies in mice.

Nuclear medicine and biology - 1 May 2014

Frindel Mathieu, Camus Nathalie, Rauscher Aurore, Bourgeois Mickaël, Alliot Cyrille, Barré Louisa, Gestin Jean-François, Tripier Raphaël, Faivre-Chauvet Alain

Abstract excerpt

INTRODUCTION: HTE1PA, a monopicolinate-N-alkylated cyclam-based ligand has previously demonstrated fast complexation process, high kinetic inertness and important thermodynamic and electrochemical stability with respect to natural copper. In this work we first developed a new synthetic route to obtain HTE1PA in good yields. Then, we investigated HTE1PA chelation properties towards copper-64 and assessed in vitro...

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PMID: 24440584
DOI: 10.1016/j.nucmedbio.2013.12.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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