Article

Enhancing Tumor Perfusion and Nanomedicine Delivery via Endogenous Nitric Oxide Release by Methyl Palmitate Nanoparticles

2026-03-04

Abstract excerpt

Despite a few clinical successes, the efficacy of cancer nanomedicines remains limited by rapid clearance by the mononuclear phagocytic system and poor permeation across the abnormal tumor vasculature. We previously showed that methyl palmitate nanoparticles (MPN) can safely and reversibly inhibit the phagocytic activity of immune cells for several hours, thereby improving tumor accumulation and the efficacy of sy...

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Literature Corpus work: dcf7052f-92a8-5c30-a38e-5d9dd2b80887
DOI: 10.64898/2026.03.02.709151

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