Article
Comprehensive Assessment of the Association between FCGRs polymorphisms and the risk of systemic lupus erythematosus: Evidence from a Meta-Analysis.
Scientific reports - 19 Aug 2016
Zhu Xiao-Wei, Wang Yong, Wei Yi-Hua, Zhao Pian-Pian, Wang Xiao-Bo, Rong Jing-Jing, Zhong Wen-Ying, Zhang Xing-Wei, Wang Li, Zheng Hou-Feng
Abstract excerpt
We performed a meta analysis to assess the relationship of FCGRs polymorphisms with the risk of SLE. Thirty-five articles (including up to 5741 cases and 6530 controls) were recruited for meta-analysis. The strongest association was observed between FCGR2B rs1050501 and SLE under the recessive genotypic model of C allele in the overall population (CC vs CT/TT, OR = 1.754, 95%CI: 1.422-2.165, P = 1.61 × 10(-7))...
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