Article
Genetic association of complement component 2 polymorphism with systemic lupus erythematosus.
Tissue antigens - 1 Aug 2015
Chen H-H, Tsai L-J, Lee K-R, Chen Y-M, Hung W-T, Chen D-Y
Abstract excerpt
Complement component 2 (C2), an early member of the classical pathway, mainly participates in apoptotic cell clearance. We hypothesize that C2 polymorphism may confer genetic susceptibility to complement dysfunction in systemic lupus erythematosus (SLE). The major aim of our study was to investigate the clinical and serological associations of C2 variants in Chinese patients with SLE. The single-nucleotide...
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