Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

B3GNT5 is a novel marker correlated with stem-like phenotype and poor clinical outcome in human gliomas.

CNS neuroscience & therapeutics - 1 Nov 2020

Jeong Hang Yeon, Park Seo-Young, Kim Hyun-Jin, Moon Seungju, Lee Seongsoo, Lee Seung Ho, Kim Sung-Hak

Abstract excerpt

AIMS: Glioblastoma multiforme (GBM) is the most lethal tumor with a median patient survival of 14 to 15 months. Glioma stem cells (GSCs) play a critical role in tumor initiation and therapeutic resistance in GBM. B3GNT5 has been suggested as the key glycosyltransferase in the biosynthesis of the (neo-) lacto series of glycosphingolipid. In this study, we evaluated the B3GNT5 expression in GSCs as well as the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioblastoma

Share to Glioma

Share to Glycosyltransferases

Share to Neoplastic Stem Cells

Share to Phenotype

Share to Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 32677340
DOI: 10.1111/cns.13439
PMCID: PMC7564194

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

B3GNT5 is a novel marker correlated with stem-like phenotype and poor clinical outcome in human gliomas.PMID 32677340Read ↗

Pan-cancer analysis of B3GNT5 with potential implications for cancer immunotherapy and cancer stem cell stemnessSemantic proximity Read ↗

A2B5 Cells from Human Glioblastoma have Cancer Stem Cell PropertiesSemantic proximity Read ↗

GNG5 is a novel oncogene associated with cell migration, proliferation, and poor prognosis in gliomaSemantic proximity Read ↗

Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicitySemantic proximity Read ↗

GALNT2 sustains glioma stem cells by promoting CD44 expressionSemantic proximity Read ↗

Targeting Wnt/β-catenin-mediated upregulation of oncogenic NLGN3 suppresses cancer stem cells in glioblastomaSemantic proximity Read ↗

Lgr5 in cancer biology: functional identification of Lgr5 in cancer progression and potential opportunities for novel therapySemantic proximity Read ↗

Knockdown of LGR5 suppresses the proliferation of glioma cells in vitro and in vivoSemantic proximity Read ↗

Bioinformatics identification of potential protein glycosylation genes associated with glioma stem cell signatureSemantic proximity Read ↗

FXYD5 promotes the growth of glioblastoma by targeting the PI3K/AKT/ACSL4 signaling axisSemantic proximity Read ↗

CCN1 Promotes Mesenchymal Phenotype Transition Through Activating NF-κB Signaling Pathway Regulated by S100A8 in Glioma Stem Cells.Semantic proximity Read ↗

miR-135b suppresses tumorigenesis in glioblastoma stem-like cells impairing proliferation, migration and self-renewal.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.