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A2B5 Cells from Human Glioblastoma have Cancer Stem Cell Properties

20 Feb 2009

Abstract excerpt

Glioblastomas, like other cancers, harbor small cell populations with the capability of sustaining tumor formation. These cells are referred to as cancer stem cells. We isolated cells expressing the surface marker A2B5 from three human glioblastomas (GBM) and showed that after grafting into nude mice, they generated dense and highly infiltrative tumors. Then, we extensively studied A2B5(+) cells isolated from 11...

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PMID: 19243384
DOI: 10.1111/j.1750-3639.2009.00269.x

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