Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GALNT2 sustains glioma stem cells by promoting CD44 expression

25 Mar 2023

Abstract excerpt

Glioblastoma (GBM) is the most prevalent and malignant brain tumor and is highly resistant to currently available treatment. In this study, we reveal that polypeptide N-acetylgalactosaminyltransferase 5 (GALNT2) expression level was elevated in GBM, IDH1 wildtype glioma, and GBM stem cells (GSCs). GALNT2 increased expression correlated with GBM patients’ unfavorable clinical outcomes. Functionally, targeting...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Caveolin-1 and cellular processes
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37000153
DOI: 10.18632/aging.204609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GALNT2 sustains glioma stem cells by promoting CD44 expressionPMID 37000153Read ↗

Low expression of GALNT6 gene in gliomas promotes immune infiltration and improves tumor prognosis using bioinformatics analysisSemantic proximity Read ↗

Identification of PDLIM1 as a glioblastoma stem cell marker driving tumorigenesis and chemoresistanceSemantic proximity Read ↗

Truncated Glioma-Associated Oncogene Homolog 1 (tGLI1) Mediates Mesenchymal Glioblastoma via Transcriptional Activation of CD44Semantic proximity Read ↗

The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem–like Properties in Glioblastoma That Contribute to TumorigenesisSemantic proximity Read ↗

Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traitsSemantic proximity Read ↗

Hypoxia-induced galectin-8 maintains stemness in glioma stem cells via autophagy regulationSemantic proximity Read ↗

Bioinformatics identification of potential protein glycosylation genes associated with glioma stem cell signatureSemantic proximity Read ↗

GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma.Semantic proximity Read ↗

NT5DC2 promotes tumorigenicity of glioma stem-like cells by upregulating fynSemantic proximity Read ↗

Pan-cancer analysis of the glycoprotein - associated gene B4GALNT4 with prognositc value and immunological role in malignant tumorsSemantic proximity Read ↗

Targeting RGS4 Ablates Glioblastoma ProliferationSemantic proximity Read ↗

GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2ASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.