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Article

Knockdown of LGR5 suppresses the proliferation of glioma cells in vitro and in vivo

31 Oct 2013

Abstract excerpt

Leucine-rich repeat containing G protein-coupled receptor 5 (LGR5), one of the target genes of the Wnt signaling pathway, has recently been identified as a marker for brain cancer stem-like cells. However, the role of LGR5 in glioma is poorly understood. The aim of the present study was to investigate the relationship between LGR5 expression and pathological grade in glioma, and the impact of LGR5 on the...

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PMID: 24172981
DOI: 10.3892/or.2013.2826

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