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Article

Unpredictability of the Fitness Effects of Antimicrobial Resistance Mutations Across Environments in Escherichia coli.

Molecular biology and evolution - 3 May 2024

Hinz Aaron, Amado André, Kassen Rees, Bank Claudia, Wong Alex

Abstract excerpt

The evolution of antimicrobial resistance (AMR) in bacteria is a major public health concern, and antibiotic restriction is often implemented to reduce the spread of resistance. These measures rely on the existence of deleterious fitness effects (i.e. costs) imposed by AMR mutations during growth...

Topics

Escherichia coli
Genetic Fitness
Mutation
Drug Resistance, Bacterial
Anti-Bacterial Agents
Models, Genetic
Environment

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38709811
DOI: 10.1093/molbev/msae086
PMCID: PMC11110942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-38709811-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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