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Article

Evolution of amoxicillin resistance of Helicobacter pylori in vitro: characterization of resistance mechanisms.

Microbial drug resistance (Larchmont, N.Y.) - 1 Dec 2014

Qureshi Nadia N, Gallaher Brandon, Schiller Neal L

Abstract excerpt

Helicobacter pylori is the major cause of peptic ulcers and gastric cancer in humans. Treatment involves a two or three drug cocktail, typically including amoxicillin. Increasing levels of resistance to amoxicillin contribute to treatment failures, and higher levels of resistance are believed to be due to multiple genetic mutations. In this study, we examined the progression of spontaneous genetic mutations that...

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Identifiers

PMID: 24901497
DOI: 10.1089/mdr.2014.0019

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