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The contribution of hereditary cancer-related germline mutations to lung cancer susceptibility

1 Jun 2020

Abstract excerpt

Background: Germline variations may contribute to lung cancer susceptibility besides environmental factors. The influence of germline mutations on lung cancer susceptibility and their correlation with somatic mutations has not been systematically investigated. Methods: In this study, germline mutations from 1,026 non-small cell lung cancer (NSCLC) patients were analyzed with a 58-gene next-generation sequencing...

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BRCA gene mutations in cancer
Cancer Genomics and Diagnostics
Lung Cancer Treatments and Mutations

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32676327
DOI: 10.21037/tlcr-19-403

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