Article
Molecular pathogenesis of hereditary lung cancer: a literature review.
Pharmacogenomics - 1 Aug 2021
Rammal Souraya, Kourie Hampig Raphael, Jalkh Nadine, Mehawej Cybel, Chouery Eliane, Moujaess Elissar, Dabar Georges
Abstract excerpt
Among all cancer types, pulmonary cancer has the highest mortality rate. Tobacco consumption remains the major risk factor for the development of lung cancer. However, many studies revealed a correlation between inherited genetic variants and predisposition to lung cancer, especially in nonsmokers. To date, genetic testing for the detection of germline mutations is not yet recommended in patients with lung cancer...
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