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Article

Pathogenic germline variants in BRCA1 and TP53 increase lung cancer risk in Chinese.

Cancer medicine - 1 Dec 2023

Wei Bing, Zhao Jiadong, Li Jun, Feng Junnan, Sun Manman, Wang Zhizhong, Shi Chao, Yang Ke, Qin Yue, Zhang Jing, Ma Jie, Dong Hui

Abstract excerpt

BACKGROUD: Multiple studies have identified pathogenic germline variants in cancer susceptibility genes (CSGs) in Chinese lung cancer patients; however, accurate assessment of these variants' contributions to cancer predisposition is always hampered by the absence of data on the prevalence of these variants in the general population. It is necessary to conduct a large-scale case-control study to identify CSGs...

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Source

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Identifiers

PMID: 37930190
DOI: 10.1002/cam4.6692
PMCID: PMC10726856

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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