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Article

A consistent approach to the genotype encoding problem in a genome-wide association study of continuous phenotypes.

PloS one - 1 Jan 2020

Kim Sunhee, Lee Chang-Yong

Abstract excerpt

In this study, we suggested a hypothesis test method that was robust to different genotype encodings in a genome-wide association analysis of continuous traits. When the population stratification is corrected for using a method based on principal component analysis, ordinally (or categorically) encoded genotypes are adjusted and turn into continuous values. Due to the adjustment of the encoded genotype, the...

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Identifiers

PMID: 32667944
DOI: 10.1371/journal.pone.0236139
PMCID: PMC7363099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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