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Article

Rank-based tests for identifying multiple genetic variants associated with quantitative traits.

Annals of human genetics - 1 Jul 2014

Li Zhengbang, Yuan Ao, Han Gang, Gao Guimin, Li Qizhai

Abstract excerpt

We consider the analysis of multiple genetic variants within a gene or a region that are expected to confer risks to human complex diseases with quantitative traits, where the trait values do not follow the normal distribution even after some transformations. We rank the phenotypic values, calculate a score to measure the trend effect of a particular allele for each marker, and then construct three statistics...

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PMID: 24942081
DOI: 10.1111/ahg.12067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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