Article
Odds ratio-based genetic algorithms for generating SNP barcodes of genotypes to predict disease susceptibility.
Omics : a journal of integrative biology - 1 Mar 2008
Chang Hsueh-Wei, Chuang Li-Yeh, Ho Chang-Hsuan, Chang Phei-Lang, Yang Cheng-Hong
Abstract excerpt
Genome-wide association analysis involving many single nucleotide polymorphisms (SNPs) data is challenging mathematically and computationally. It is time consuming to classify the combination of multilocus genotypes into high- and low-risk groups without false positive and negative errors. Hence, we propose the odds ratio-based genetic algorithms (OR-GA) method that uses the odds ratio as a new quantitative...
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