Article
On coding genotypes for genetic markers with multiple alleles in genetic association study of quantitative traits.
BMC genetics - 21 Sept 2011
Wang Tao
Abstract excerpt
BACKGROUND: In genetic association study of quantitative traits using F(∞) models, how to code the marker genotypes and interpret the model parameters appropriately is important for constructing hypothesis tests and making statistical inferences. Currently, the coding of marker genotypes in building F(∞) models has mainly focused on the biallelic case. A thorough work on the coding of marker genotypes and...
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