Article
A generalized Kruskal-Wallis test incorporating group uncertainty with application to genetic association studies.
Biometrics - 1 Jun 2013
Acar Elif F, Sun Lei
Abstract excerpt
Motivated by genetic association studies of SNPs with genotype uncertainty, we propose a generalization of the Kruskal-Wallis test that incorporates group uncertainty when comparing k samples. The extended test statistic is based on probability-weighted rank-sums and follows an asymptotic chi-square distribution with k - 1 degrees of freedom under the null hypothesis. Simulation studies confirm the validity and...
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