Article
Factors affecting the effective number of tests in genetic association studies: a comparative study of three PCA-based methods.
Journal of human genetics - 1 Jun 2011
Wen Shu-Hui, Lu Zhi-Sheng
Abstract excerpt
The number of tested marker becomes numerous in genetic association studies (GAS) and one major challenge is to derive the multiple testing threshold. Some approaches calculating an effective number (M(eff)) of tests in GAS were developed and have been shown to be promising. As yet, there have be...
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