Article
Glioblastoma multiforme: Metabolic differences to peritumoral tissue and IDH-mutated gliomas revealed by mass spectrometry imaging.
Neuropathology : official journal of the Japanese Society of Neuropathology - 1 Dec 2020
Kampa Judith M, Kellner Udo, Marsching Christian, Ramallo Guevara Carina, Knappe Ulrich J, Sahin Mikail, Giampà Marco, Niehaus Karsten, Bednarz Hanna
Abstract excerpt
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor. High infiltration rates and poor therapy responses make it the deadliest glioma. The tumor metabolism is known to differ from normal one and is influenced through various factors which can lead to longer survival. Metabolites are small molecules (< 1500 Da) that display the metabolic pathways in the tissue. To determine the metabolic...
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