Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluating angiotensin-converting enzyme 2-mediated SARS-CoV-2 entry across species.

The Journal of biological chemistry - 1 Jan 2000

Zhang Hong-Liang, Li Yu-Ming, Sun Jing, Zhang Yu-Yuan, Wang Tong-Yun, Sun Ming-Xia, Wang Meng-Hang, Yang Yue-Lin, Hu Xiao-Liang, Tang Yan-Dong, Zhao Jincun, Cai Xuehui

Abstract excerpt

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic represents a global threat, and the interaction between the virus and angiotensin-converting enzyme 2 (ACE2), the primary entry receptor for SARS-CoV-2, is a key determinant of the range of hosts that can be infected by the virus. However, the mechanisms underpinning ACE2-mediated viral entry across species remains unclear. Using infection...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme 2
Share to Cats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chiroptera

Share to Macaca mulatta

Share to Pandemics

Share to Spike Glycoprotein, Coronavirus

Share to Virus Internalization

Source

Open in PubMed Open full text

Identifiers

PMID: 33610551
DOI: 10.1016/j.jbc.2021.100435
PMCID: PMC7892319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluating angiotensin-converting enzyme 2-mediated SARS-CoV-2 entry across species.PMID 33610551Read ↗

Cell entry of SARS-CoV-2 conferred by angiotensin-converting enzyme 2 (ACE2) of different speciesSemantic proximity Read ↗

Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2Semantic proximity Read ↗

Broad and Differential Animal Angiotensin-Converting Enzyme 2 Receptor Usage by SARS-CoV-2.Semantic proximity Read ↗

Functional and Genetic Analysis of Viral Receptor ACE2 Orthologs Reveals a Broad Potential Host Range of SARS-CoV-2Semantic proximity Read ↗

Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domainsSemantic proximity Read ↗

Angiotensin-converting enzyme 2 (ACE2) proteins of different bat species confer variable susceptibility to SARS-CoV entry.Semantic proximity Read ↗

Receptor utilization of angiotensin‐converting enzyme 2 (ACE2) indicates a narrower host range of SARS‐CoV‐2 than that of SARS‐CoVSemantic proximity Read ↗

Broad host tropism of ACE2-using MERS-related coronaviruses and determinants restricting viral recognitionSemantic proximity Read ↗

Broad host tropism of ACE2-using MERS-related coronaviruses and determinants restricting viral recognitionSemantic proximity Read ↗

In silico comparison of SARS-CoV-2 spike protein-ACE2 binding affinities across species and implications for virus originSemantic proximity Read ↗

Predicting susceptibility to SARS-CoV-2 infection based on structural differences in ACE2 across species.Semantic proximity Read ↗

Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.