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Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains

27 Jul 2022

Abstract excerpt

Viral spillover from animal reservoirs can trigger public health crises and cripple the world economy. Knowing which viruses are primed for zoonotic transmission can focus surveillance efforts and mitigation strategies for future pandemics. Successful engagement of receptor protein orthologs is necessary during cross-species transmission. The clade 1 sarbecoviruses including Severe Acute Respiratory...

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PMID: 35895696
DOI: 10.1371/journal.pbio.3001738

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