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Article

Detecting fitness epistasis in recently admixed populations with genome-wide data.

BMC genomics - 11 Jul 2020

Ni Xumin, Zhou Mengshi, Wang Heming, He Karen Y, Broeckel Uli, Hanis Craig, Kardia Sharon, Redline Susan, Cooper Richard S, Tang Hua, Zhu Xiaofeng

Abstract excerpt

BACKGROUND: Fitness epistasis, the interaction effect of genes at different loci on fitness, makes an important contribution to adaptive evolution. Although fitness interaction evidence has been observed in model organisms, it is more difficult to detect and remains poorly understood in human populations as a result of limited statistical power and experimental constraints. Fitness epistasis is inferred from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32652930
DOI: 10.1186/s12864-020-06874-7
PMCID: PMC7353720

Genes

ADAR
IFI44
S1PR1
VCAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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