Article
Prickle2 and Igsf9b Coordinately Regulate the Cytoarchitecture of the Axon Initial Segment
1 Jan 2020
Abstract excerpt
Prickle2 has been identified in genetic studies of subjects with autism spectrum disorder (ASD) and epilepsy, but the pathological mechanism of Prickle2 remains to be fully understood. Proteomic analysis of Prickle2 with mass spectrometry revealed twenty-eight Prickle2 interactors, including immunoglobulin superfamily member 9b (Igsf9b), in the brain. Here, because Igsf9 family proteins are associated with...
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