Article

Overlap in synaptic neurological condition susceptibility pathways and the neural pannexin 1 interactome revealed by bioinformatics analyses

2019-10-11

Abstract excerpt

<h4>ABSTRACT</h4> Many neurological conditions exhibit synaptic impairments, suggesting mechanistic convergence. Additionally, the pannexin 1 (PANX1) channel and signalling scaffold is linked to several of these neurological conditions and is an emerging regulator of synaptic development and plasticity; however, its synaptic pathogenic contributions are relatively unexplored. To this end, we explored connections...

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Literature Corpus work: f7bf9591-f2bf-5a89-b67f-d665cf9828d1
DOI: 10.1101/801563

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