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An individualized transcriptional signature to predict the epithelial-mesenchymal transition based on relative expression ordering

8 Jul 2020

Abstract excerpt

The epithelial-mesenchymal transition (EMT) process is involved in cancer cell metastasis and immune system activation. Hence, identification of gene expression signatures capable of predicting the EMT status of cancer cells is essential for development of therapeutic strategies. However, quantitative identification of EMT markers is limited by batch effects, the platform used, or normalization methods. We...

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PMID: 32639951
DOI: 10.18632/aging.103407

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