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Identifying global expression patterns and key regulators in epithelial to mesenchymal transition through multi-study integration

26 Jun 2017

Abstract excerpt

BACKGROUND: Epithelial to mesenchymal transition (EMT) is the process by which stationary epithelial cells transdifferentiate to mesenchymal cells with increased motility. EMT is integral in early stages of development and wound healing. Studies have shown that EMT could be a critical early event in tumor metastasis that is involved in acquisition of migratory and invasive properties in multiple carcinomas....

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PMID: 28651527
DOI: 10.1186/s12885-017-3413-3

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