Article

Testing the Gene Expression Classification of the EMT Spectrum

2018-10-25

Abstract excerpt

The epithelial-mesenchymal transition (EMT) plays a central role in cancer metastasis and drug resistance – two persistent clinical challenges. Epithelial cells can undergo a partial or full EMT, attaining either a hybrid epithelial/mesenchymal (E/M) or mesenchymal phenotype, respectively. Recent studies have emphasized that hybrid E/M cells may be more aggressive than their mesenchymal counterparts. However, mech...

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Literature Corpus work: 6dd002d6-f698-59be-b040-63dc3064269e
DOI: 10.1101/452508

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