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Article

Testing the gene expression classification of the EMT spectrum.

Physical biology - 18 Jan 2019

Jia Dongya, George Jason T, Tripathi Satyendra C, Kundnani Deepali L, Lu Mingyang, Hanash Samir M, Onuchic José N, Jolly Mohit Kumar, Levine Herbert

Abstract excerpt

The epithelial-mesenchymal transition (EMT) plays a central role in cancer metastasis and drug resistance-two persistent clinical challenges. Epithelial cells can undergo a partial or full EMT, attaining either a hybrid epithelial/mesenchymal (E/M) or mesenchymal phenotype, respectively. Recent studies have emphasized that hybrid E/M cells may be more aggressive than their mesenchymal counterparts. However,...

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Identifiers

PMID: 30557866
DOI: 10.1088/1478-3975/aaf8d4
PMCID: PMC7179477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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