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Article

Histopathologic features of breast cancer in Li-Fraumeni syndrome.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Mar 2021

Kuba M Gabriela, Lester Susan C, Bowman Teresa, Stokes Samantha M, Taneja Krishan L, Garber Judy E, Dillon Deborah A

Abstract excerpt

Breast cancer is the most common malignancy in female patients with Li-Fraumeni syndrome (LFS), a rare autosomal dominant hereditary syndrome characterized by germline TP53 mutations. Recent studies have shown that the majority of these tumors are estrogen receptor (ER) positive with frequent HER2 co-expression. However, the morphologic features of these tumors have not been as well studied as other...

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Identifiers

PMID: 32636452
DOI: 10.1038/s41379-020-0610-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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