Ductal carcinoma in situ: morphology-based knowledge and molecular advances.

doi:10.1097/PAP.0b013e3182976ed5

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Article

Ductal carcinoma in situ: morphology-based knowledge and molecular advances.

Advances in anatomic pathology - 1 Jul 2013

Ross Dara S, Wen Yong Hannah, Brogi Edi

Abstract excerpt

Ductal carcinoma in situ (DCIS) is an established precursor of invasive breast carcinoma. Immunoperoxidase stains for selected markers can assist pathologists in the diagnosis of challenging ductal epithelial proliferations, but they cannot replace morphologic evaluation as the primary and critical assessment of this disease. Molecular studies provide further insight into how DCIS progresses to invasive carcinoma...

Topics

Biomarkers, Tumor
Biopsy
Breast Neoplasms
Carcinoma, Intraductal, Noninfiltrating
Cell Proliferation
Disease Progression
Female
Genetic Predisposition to Disease
Genetic Techniques
Humans
Immunohistochemistry
Phenotype
Predictive Value of Tests
Prognosis
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 23752083
DOI: 10.1097/PAP.0b013e3182976ed5

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