Article
Common variants in LAMC1 confer risk for pelvic organ prolapse in Chinese population.
Hereditas - 7 Jul 2020
Chen Juan, Li Lei, Lang Jinghe, Zhu Lan
Abstract excerpt
BACKGROUND: Pelvic organ prolapse (POP) affects around 15% of postmenopausal women in China. Although it has been widely accepted that genetic variants could confer risk for POP, the genetic susceptibility variants remain largely unknown. Previous studies indicated that LAMC1, which encodes the laminin gamma 1 chain and is critical for extracellular matrix, might be a susceptibility gene for POP. The study is to...
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